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Anhui
Long-term effective
2019-08-26 14:12
359
hfhongmei(Mr.)
Anhui
1117, Lanchou Mansion, No.135, North Mengcheng Road, 230041, Hefei, Anhui, China
Product Description:
Product Name: Sitagliptin phosphate monohydrate CAS NO: 654671-77-9
Synonyms:
7-[(3R)-3-Amino-1-oxo-4-(2,4,5-trifluorophenyl)Butyl]-5,6,7,8-tetrahydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazinephosphatemonohydrate;
7-((3R)-3-Amino-4-(2,4,5-trifluorophenyl)butanoyl)-3-(trifluoromethyl)-5,6,7,8-tetrahydro-1,2,4- triazolo(4,3-a)pyrazine monophosphate monohydrate;
3(R)-3-amino-1-[3-(trifluoromethyl)-5H,6H,7H,8H[1,2,4]triazolo[4,3-a]pyrazin-7-yl]-4-(2,4,5-trifluorophenyl)butan-1-one phosphate monohydrate;
(2R)-4-oxo-4-[3-(trifluoromethyl)-5,6-dihydro[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl]-1-(2,4,5-trifluorophenyl)butan-2-amine dihydrogenphosphate monohydrate;
(R)-3-Amino-1-(3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)-4-(2,4,5-trifluorophenyl)butan-1-one phosphate hydrate;
1,2,4-Triazolo(4,3-a)pyrazine,7-((3R)-3-amino-1-oxo-4-(2,4,5-trifluorophenyl)butyl)-5,6,7,8- tetrahydro-3-(trifluoromethyl)-, phosphate (1:1) monohydrate;
1-Butanone, 3-amino-1-[5,6-dihydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazin-7(8H)-yl]-4-(2,4,5-trifluorophenyl)-, (3R)-, phosphate, hydrate (1:1:1);
Sitagliptin phosphate ;
Sitagliptin monohydrate ;
Sitagliptin phosphate hydrate;
Chemical & Physical Properties:
Appearance : White or almost white powder
Assay : ≥99.0%
Density: N/A
Melting point: 216-219℃
Boiling Point: 529.9℃ at 760 mmHg
Flash Point: 274.3℃
Refractive Index: N/A
Vapor Pressure: 0.0mmHg at 25°C
PSA: 173.84000
LogP:1.66180
Solubility: DMSO.
Category: API;Inhibitor;-;Inhibitors;
Safety Information
HS Code: 2933990090
Storage:Stored in a cool and dry well-closed container. Keep away from moisture and strong light/heat.
Application: It is used to produce sitastatin phosphate, a new inhibitor of dipeptidyl peptidase-4 (DPP-4), which can improve the human body's ability to reduce hyperglycemia.
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